DNA Genotype Test

£358.80

Explore a comprehensive range of over 300 trait, health, and wellness reports to uncover valuable insights about yourself. Gain a deep understanding of various aspects related to your traits, physical well-being, and overall health.

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Description

What can I expect from undergoing a DNA Genotype Test?

DNA, the genetic material that carries molecular-level information, plays a crucial role in predicting various aspects such as physical appearance, physiological processes, and disease risk.

This comprehensive DNA Genotype Test offers a once-in-a-lifetime opportunity to gain valuable insights into nutrition, traits, fitness, and health based on your unique genetic blueprint. With over 300 reports included, this test analyzes markers in your genetic profile to identify your distinctive qualities and traits.

By providing a simple saliva sample, you can unlock a wealth of knowledge about yourself, enabling the creation of personalized wellness products and plans. This empowers you to make informed decisions for a healthier future.

Please note that the report will be delivered within 4 weeks after your sample arrives at our laboratory.

Additional reports included in the test are as follows:

  1. Ancestry: Uncover your roots and trace your lineage through genetic genealogy. Explore your ancestry across 7 historic eras and 150 modern population clusters.
  2. Pharmacogenomics: This report allows medical practitioners to personalize your medications and predict potential drug reactions for over 130 medications. By analyzing your genomic profile and studying over 2000 targets, this report serves as a guide to identify optimal drugs, drugs to avoid, and dosage requirements.

What information will be included in my DNA report?

The DNA report encompasses over 300 different traits organized into 20 categories. Here are some of the main categories covered in the report:

NUTRI GENOMICS
  • Response To Macronutrients
  • Food Sensitivities
  • Eating Perceptions
  • Psychology Of Eating
  • Weight Loss Management
FITNESS GENOMICS
  • Endurance Training Attributes
  • Flexibility
  • Exercise Response
ALLERGY
  • Food Allergies
  • Skin Allergies
  • Nasal Allergies
ADDICTION
  • Alcohol Addiction
  • Cannabis Addiction
  • Cocaine Addiction
  • Heroin Addiction
  • Nicotine Addiction
  • Opioid Addiction
HAEMATOLOGICAL DISEASES
  • Morphology And Texture
  • Photoaging
  • Chronic Inflammatory Conditions
  • Autoimmune Disorders
OPHTHALMOLOGY
  • Refractive Error
  • Corneal Disorders
  • Ophthalmic Disorders
  • Orbital Disorders
  • Retinal Disorders
DERMATOLOGY
  • Morphology and Texture
  • Photoaging
  • Chronic Inflammatory Conditions
  • Autoimmune Disorders
GASTROINTESTINAL DISORDERS
  • Digestive Tract Disorders
  • GI Accessory Disorders
NEUROLOGY
  • Learning And Developmental Disorders
  • Neurodegenerative Disorders
  • Demyelinating Disorders
  • Eating Disorders
  • Musculoskeletal Disorders
  • Sleep Disorders
  • Psychiatric Disorders
  • Nervous System Disorders
  • Chronic Neurological Disorders
  • Anxiety Disorders
HORMONAL DISORDERS
  • Pituitary Disorders
  • Thyroid Disorders
  • Paediatric Disorders
  • Adrenal Disorders
  • Osteoporosis And Bone Health Disorders
  • Diabetes
  • Women’s Health
  • Men’s Health
PERSONALITY TRAITS
  • Cognitive Ability
  • Extraversion
  • Openness
  • Agreeableness
  • Conscientiousness
  • Neuroticism
RENAL DISORDERS
  • Endocrine And Metabolic Disorders
  • Congenital Renal and Genitourinary Condition
  • Chronic Renal Conditions
  • Inherited Renal Conditions
  • Glomerular Disorders
  • Congenital Renal Diseases
  • Systemic Lupus Erythematosus
  • Urinary Calculi
CIRCADIAN RHYTHM ASSOCIATED TRAITS
  • Sleep Disorders
  • Chronotype
  • Sleep Characteristics

 

LIFESTYLE GENOMICS 
  • Cardiac
  • Diabetes
  • Weight Management
PULMONARY DISORDER
  • Respiratory Failure
  • Infectious Disease
  • Interstitial Lung
  • Deficiency Disorders
  • Inflammation Disorders
BONE HEALTH AND DISEASES
  • Bone Health and Density
  • Joint Disorders
  • Bone disorders

 

What information does my Pharmacogenetics (PGx) report contain?

Pharmacogenetics focuses on the study of the relationship between genetic variations and how our bodies respond to medications. It encompasses both Pharmacokinetics (how our bodies process the drug) and Pharmacodynamics (how the drug affects our bodies). Genetic variations, such as haplotypes or genotypes, can impact drug metabolism, transport, response, and reactions.

The PGx report analyzes variants in pharmacogenomics genes to assist clinicians in determining the effectiveness of a medication for you and the likelihood of experiencing side effects, adverse drug reactions (ADRs), or toxicity to specific medications. By assessing the risk of an ADR before a patient takes a medication, the PGx test enhances patient safety and reduces costs for healthcare facilities.

Please note that this report is intended for investigational use only and should be interpreted by a qualified and licensed medical practitioner. It does not constitute medical advice, diagnosis, or treatment. Pharmacogenetics is just one of several factors, including age, sex, ethnicity, and medical history, that contribute to a patient’s response to medication.

Please refer to the table below for the different categories and drugs included in the report:

Category  Drug
Diabetes Glibenclamide, Gliclazide, Glimepiride, Tolbutamide
Cardiovascular Disease Amiodarone, Atenolol, Atorvastatin, Bisoprolol, Carvedilol, Clonidine, Clopidogrel, Disopyramide, Flecainide, Fluvastatin, Metoprolol, Nebivolol, Prasugrel, Propafenone, Quinidine, Ranolazine, Simvastatin, Sotalol, Ticagrelor, Triveram, Vernakalant
Attention Deficit Hyperactivity Disorder (ADHD) Atomoxetine, Methylphenidate
COPD Umeclidinium
Gastrointestinal Disorders Dexlansoprazole, Esomeprazole, Lansoprazole, Metoclopramide, Omeprazole, Pantoprazole, Rabeprazole
Immunological Disorders Cevimeline
Neurological Disorders Deutetrabenazine, Donepezil, Galantamine, Tetrabenazine, Valbenazine
Oncology Belinostat, Capecitabine, Fluorouracil, Gefitinib, Irinotecan, Nilotinib, Ondansetron, Pazopanib, Rucaparib, Tamoxifen, Tegafur, Tropisetron
Pain Carisoprodol, Codeine, Elagolix, Naproxen, Oxycodone, Tramadol
Psychiatric Amoxapine, Aripiprazole, Aripiprazole Lauroxil, Brexipiprazole, Brivaracetam, Cariprazine, Citalopram, Clobazam, Clozapine, Desipramine, Desvenlafaxine, Duloxetine, Escitalopram, Fluoxetine, Flupenthixol, Fluphenazine, Fluvoxamine, Haloperidol, Iloperidone, Lacosamide, Moclobemide, Nefazodone, Nortriptyline, Olanzapine, Paliperidone, Paroxetine, Perphenazine, Pimozide, Pitolisant, Propranolol, Protriptyline, Quetiapine, Risperidone, Sertindole, Sertraline, Thioridazine, Venlafaxine, Vortioxetine, Zuclopenthixol
Renal Disorders Lesinurad, Mirabegron, Tolterodine
Respiratory Tract Arformoterol, Indacaterol
Rheumatoid Arthritis Upadacitinib,
Infectious Diseases Atazanavir, Dolutegravir, Efavirenz, Flucytosine, Peg-Interferon-Alpha, Raltegravir, Ribavirin, Telaprevir, Voriconazole
Muscle Disease Amifampridine, Amifampridine Phosphate, Tolperisone
Inflammatory Disease Aceclofenac, Aspirin, Celecoxib, Diclofenac, Dipyrone, Flurbiprofen, Ibuprofen, Indomethacin, Lornoxicam, Lumiracoxib, Meloxicam, Nabumetone, Piroxicam, Tenoxicam

What information does my Ancestry report contain?

As humans, we have always been curious about our origins and have a strong desire to trace back our ancestral roots. Ancestry reports provide a fascinating glimpse into our estimated origin story. The evolutionary theories of human history suggest that our species originated in Africa and subsequently migrated to Eurasia. Throughout history, the survival of the human race has been challenged by various factors such as natural disasters and the rise and fall of civilizations. These events have shaped the migration patterns of different populations, leading to the diversification of ethnicities. Despite these changes, our DNA has remained constant over the course of more than 50,000 years. Each of us carries a unique DNA sequence that can unveil our ancestral origins across different historic eras and trace the migratory paths taken by our ancestors.

The Ancestry report includes different components:

  1. Ancient Ancestry: This report is based on Ancestry Informative Markers (AIMs) and provides insights into your genetic heritage since ancient times. It covers a time span ranging from the Paleolithic age to the current Post-Ancient Age. The report shows the percentage of your genome inherited from each of the 7 eras, as well as the specific regions associated with those eras.
  2. Lineage: This report reveals migration patterns in your paternal and maternal lineages based on your genetic markers. It maps out a migration journey by tracing DNA haplogroups, revealing your ancestral path up to the recorded common ancestor.
  3. Modern Ancestry: This report evaluates your ancestry by comparing your genetic profile with our reference datasets of 150+ populations. These populations are grouped into 37 clusters at sub-continental or regional levels. The report highlights the proportion of various modern populations present in your genetic makeup.

These reports provide intriguing insights into your ancestral history, allowing you to connect with your roots and understand the diverse genetic heritage that contributes to who you are today.

How the process works

Whether you opt for a home test or choose to have your sample collected by one of our skilled phlebotomists, our blood tests are designed to be simple and efficient.

  1. Take the test: Conveniently perform the test in the comfort of your own home or visit one of our designated testing locations.
  2. Send us your sample: For our at-home tests, we provide pre-paid postage, making it easy for you to send us your sample for analysis.
  3. Receive your results: Once your sample has been analyzed, we provide a secure link to access your doctor-validated personal results. You can review your results at your convenience and gain valuable insights into your health and well-being.

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